Natural Abs are not germ-specific whereas acquired Abs are specifically directed at the invading pathogen. Since 2014, however, he has been trying (apparently unsuccessfully) to develop his so-called universal vaccine. His argument sounds a lot like an argument Andrew Wakefield once made for MMR. But only ongoing clinical trials will show whether vaccinated individuals recognise SARS-CoV-2 variants differently, and whether mutations decrease vaccine protection in some vaccinated individuals. Basically, Dr. Vanden Bossches open letter is a mess that directly channels Andrew Wakefield. Bij de vorming van de Verenigde Nederlandse Staten in 1789 vormden zij de eerder conservatieve fractie tegenover de vonckisten. As I like to say, if you ever write anything that channels Andrew Wakefield, you really should reconsider your life choices. In the first two letters alone, he uses some variation of the phrase "it is reasonable to assume" at least seven times. Dr. Geert Vanden Bossche is a veterinary doctor who also has a Ph.D. in virology. ", While a universal vaccine that could eradicate virtually any disease certainly sounds great, no evidence exists that such a vaccine has ever successfully been developed. Hence, it also offers unprecedented advantages in terms of safety, convenience and cost-effectiveness. Volgens Vanden Bossche kunnen onvolledige vaccinaties ertoe leiden dat het coronavirus sneller resistent wordt, met andere woorden bestand tegen het vaccin. ), lets just review what Wakefield claimed about the MMR vaccine back in 2019. This inevitably leads to enhanced natural selection and adaptation of more invasive immune escape variants, 2/4 6 37 Geert Vanden Bossche is een Belgische dierenarts[1], viroloog[1], zelfverklaard mRNA-vaccinatie specialist en onafhankelijk onderzoeker en adviseur op het gebied van vaccins. Its here that his LinkedIn profile helps, specifically, his entry under Univac: I founded Univac as [sic] inventor of a new vaccine technology which I subsequently further developed as CSO of the Company. Hij wijst erop dat hij geen soort van hobby viroloog is zoals hij wordt weggezet in de media en benoemt zijn ervaringen en diplomas waaronder bepaalde zaken die niet veel Vlamingen hem hebben voorgedaan. In an effort to sidestep this self-evident solution, Vanden Bossche seems to have made up a second mechanism to stoke fear over COVID-19 vaccines. Het onderzoek ernaar is nog zeer pril. Selecting targeted mutations in the S protein is, therefore, the way to go in order for the virus to enhance its infectiousness in candidates that are prone to geting [sic] the disease because of a transient weakness of their innate immune defense. As a result, Im posting this. Ik heb een lijst van professoren die mijn bezorgdheden delen en zal deze publiceren. Daarna werd hij hoofd van het Vaccine Development Office van het Duitse Centrum voor Infectieonderzoek. 39. First of all, note how Dr. Vanden Bossche is conflating vaccine-induced immunity with natural immunity. However, Dr. Vanden Bossches claims to have worked with the Gates Foundation, GAVI, and other vaccine-related enterprises does seem to be legitimate, which makes me wonder: Has he gone crank or is he a grifter? 70 ID:bdLlFOqq0 >>1 3 . See what I mean? Nirenberg goes further and notes that the antibody titers induced by vaccines are MUCH higher than those seen after infection, and we see hallmarks of memory responses induced by these vaccines from even a single dose, suggesting that, even though there is a decrease in neutralization by vaccine-induced SARS-CoV-2 antibodies, that might not portend a loss in protection. Unfortunately, Dr. Vanden Bossches open letter has gone viral and is being spread on antivaccine social media everywhere as slam dunk evidence that COVID-19 vaccines will cause a global catastrophe by selecting for the evolution of highly transmissible and deadly variants of COVID-19 that will escape immunity due to vaccines. 53(4) . Wat beweert hij nu precies en wat is er van aan? Ook de theorie achter zijn betoog klopt niet: een vaccin onderdrukt het aangeboren immuunsysteem niet, en onvolledig gevaccineerde mensen helpen een virus niet om te veranderen. Integendeel: die strategie helpt net om een epidemie onder controle te krijgen. Aert van den Bossche or the Master of the Crispinus and Crispinianus-Legend (also known as Aert Panhedel, Aert van Panhedel, Arnoul de Panhedel, Arnoul Vanden Bossche and Harnoult van den Boske) was an Early Netherlandish painter of altarpieces, active in Brussels and Bruges in the late 15th century. Snoeck: Je zou al een zeer complexe virusmutatie op verschillende vlakken nodig hebben. mRNA-vaccins werden al volop ontwikkeld vr COVID-19 uitbrak (En coronavaccins zoals Pfizer en Moderna maken gebruik van messenger-RNA dat in de cellen van de mens eiwitten aanmaakt van virusuitsteeksels, red.). Ultimately, most vaccines are based on a recombinant spike protein sequence. This makes no sense, Yale's Omer told us. The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species. 721. Racing against the clock, I am completing my scientfic [sic] manuscript, the publication of which is, unfortunately, likely to come too late given the ever increasing threat from rapidly spreading, highly infectious variants. Relatiedeskundige Rika Ponnet beantwoordt de vraag van de week: "Moeder-dochterrelaties zijn meest complexe relaties Dan toch geen Europees verbod op benzine- en dieselwagens? As I noted when Andrew Wakefield explicitly used the example of Mareks disease to claim that a leaky vaccine to MMR would cause a global catastrophe by selecting for deadly measles variants, yes, a leaky vaccine changes the selective pressure and permits the evolution of highly virulent strains because the virus retains the ability to continue to spread among vaccinated populations, leading to the vaccine selecting for the most virulent mutations. Je laten vaccineren lijkt wel het nieuwe dopen. To follow Dr . Paradoxically, the only intervention that could offer a perspective to end this pandemic (other than to let it run its disastrous course) is VACCINATION. #COVID19 #openthedebate, Geert Vanden Bossche (@GVDBossche) March 7, 2021. Bij herpes bijvoorbeeld. Massavaccinatie middenin een pandemie, (zorgt) voor druk op virusstammen (om te muteren, veranderen naar een nieuwe vorm dus, red. At birth, our innate immune system is unexperienced but well-established. Mensen die gevaccineerd zijn, voelen zich soms een dag niet goed, met koorts bijvoorbeeld. I noted then that there was no evidence that mass vaccination with MMR had produced variants of the measles vaccine resistant to the immunity produced by the vaccine, just as I note now that there is as yet no evidence that SARS-CoV-2 variants are resistant to the immunity produced by current COVID-19 vaccines. He also points out that there is new research challenging the previous dogma that leaky vaccines always select for more virulent strains of pathogen and cannot produce herd immunity. Reading the letter, what it reminded me, more than anything else, is an article that Andrew Wakefield wrote about the MMR vaccine and measles, published a few months before the pandemic hit. 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Jul 4, 2022 Replying to @GVDBossche This suboptimal immune pressure exerted by large populations is now confronted with a viral variant! At this point, I will also mention that, because Ed Nirenberg produced an excellent rebuttal of Dr. Vanden Bossches mangling of immunology in his letter, Ill stick more to my lane (mostly, anyway), although there will be some overlap. Vanden Bossche stelt het voor alsof een virus na slechts enkele mutaties al bestand kan zijn tegen een vaccin en zo erg dodelijk kan worden. This sharply contrasts with conventional targeting of natural immune responses as induced by conventional vaccines. "Zelfs van levende kunstenaars als Dillemans worden er tekeningen Herman De Croo gaat extra vergoeding bovenop pensioen schenken aan Stichting tegen Kanker, Mannen getuigen over seksueel geweld tijdens de oorlog: "Het is erger dan afgeranseld worden", Zus van Olivier Vandecasteele reageert op uitspraak Grondwettelijk Hof: "Beste dat wij konden verwachten", Acteur Tom Sizemore (61), bekend van "Saving private Ryan" en "Heat", overleden. "Dat is een compleet ander mechanisme. Hes selling his idea of a vaccine designed to activate natural killer cells. NK cells are pathogen destroying cells that are part of the innate immune system. In any case, I got a particularly strong brave maverick vibe from this passage: While there is no time to spare, I have not received any feedback thus far. Variants are "a thing to keep an eye on," Saad Omer, an epidemiologist who serves as director of the Yale Institute for Global Health, told us in a phone interview. De experten zitten op twitter fact-checkers te liken en roepen mij op aan de juiste kant te staan. An example of a leaky vaccine is the vaccine against Mareks disease, highly contagious and deadly viral disease of chicken that is a major problem in the poultry industry, and Dr. Vanden Bossche relies on this precedent, as Nirenberg explains: For a moment though, lets entertain the notion that the vaccines are leaky. Add a bio, trivia, and more. De tekst is beschikbaar onder de licentie. Eerst werd het nog genegeerd maar door de vele vragen hierover voelde VRTNWS zich toch genoodzaakt te reageren op haar website. The molecular weight cut-off of microcapsules is determined by the reaction between alginate and polylysine. Er is dus geen reden om aan te nemen dat de coronavaccins tot een massale sterftegolf zouden kunnen leiden. 23.4K. Honderdduizenden mensen zagen zijn boodschap intussen. Na de eerste Franse inval in de Zuidelijke Nederlanden verdwenen zij van het toneel. There's even grift likely involved! Of course, the type of vaccines to be used would be completely different from conventional vaccines in that theyre not inducing the usual suspects, i.e., B and T cells, but NK cells. Fact-checkers noemt Vanden Bossche marionetten van een georkestreerde smaadcampagne die zich als leek willen mengen in zulk complex gegeven als virologie. The solution to that risk is to vaccinate as many people as quickly as possible, thereby reducing both transmission of the virus and the number of environments in which mutations could occur. He invokes the discovery of variants currently in circulation that have altered portions of the spike protein the target of COVID-19 vaccine implying that these observations lead credence to his hypothesis. Please read and share: https://t.co/0Fupw9JInP #COVID19 pic.twitter.com/I24mSjpVKM, Geert Vanden Bossche (@GVDBossche) March 6, 2021. Zowel bij de experten, bij de politiek als binnen de media zouden er dan logischerwijs evaluaties moeten volgen van hoe en waarom men zo fout was. That. ", On top of the false notion that imperfect vaccine antibodies will hamper the overall immune system on its own, Vanden Bossche claims that the prolonged lockdowns have left our innate immune system out of practice. Maar een vaccin werkt niet rechtstreeks in op een virus." On March 6, 2021, a Belgian veterinarian named Geert Vanden Bossche published an open letter"to all authorities, scientists and experts around the world" asserting that, in his expert analysis, the current global COVID-19 vaccination program will "wipe out large parts of our human population." TV Shows. Integendeel, de uitbraken zijn onder controle gebracht.. Al was het maar om het lezerspubliek niet langer voor de gek te houden besluit Vanden Bossche. However, as we age, we will increasingly face situations where our innate immunity (often called the first line of immune defense) is not strong enough to halt the pathogen at the portal of entry (mostly mucosal barriers like respiratory or intestinal epithelia). So it is scientifically based but the conclusions of the chapters are accessible to laymen as is the entire chapter "Answers to Key Questions" I think that grifters recognize fellow grifters, and Frei recognized that Dr. Vanden Bossche is stoking fear of existing COVID-19 vaccines to produce a sales rationale for his own NK-based vaccine, just as Andrew Wakefield stoked fear of the MMR in order to support his own measles vaccine. Vervolgens wijst hij erop dat de gekende experten nooit ge-fact-checkt worden. Aangezien het geen debat betreft maar een reactie op een reactie in de vorm van een monoloog is het als leek moeilijk in te schatten wie er wetenschappelijk gelijk heeft. Before he gets to his concerns, like anyone spreading antivaccine disinformation, whether as an antivaxxer or someone whos misguided, Dr. Vanden Bossche, like RFK Jr., must proclaim himself so very firmly not antivaccine: I am all but an antivaxxer. There you have it, the lone scientific maverick who is the only one willing to speak out about against a horror being perpetrated by conventional medicine and science that they dont want you to know about or discuss, a horror thats so urgent that he must speak now. Leroux-Roels duikt tijdens ons gesprek in de databank clinicaltrials.com, waar alle wetenschappelijke studies geregistreerd worden. Reality aside, invoking the innate immune system provides two rhetorical benefits. "Natural infection kills. p.528-531. Speaking with McGill University's Office for Science and Society, Dr. Paul Offit, a doctor and vaccine scientist who serves as director of the Vaccine Education Center at the Children's Hospital of Philadelphia, explained that no matter where one is or was quarantined, you are still constantly exposed to microorganisms challenging your immune system. He claims that the vaccines will destroy our bodies' ability to use our innate immune system (which produces, among other things, non-specific cells capable of clearing a wide variety of infectious material from the body) to fight off the variants vaccines allegedly could not. Zijn pleidooi werd vooral opgevangen en verspreid in de vaccin-kritische beweging. De vier wetenschappers die we contacteerden, begrijpen niet hoe daar ook maar iets van zou kunnen kloppen. The situation is just too urgent! Feb 18 Replying to @RespectingFA My intention was to write a scientific work to provide my fellow scientists with the indispensable insight that they now so often lack.