67% of reviewers reported a positive effect, while 13% reported a negative effect. Please enable it to take advantage of the complete set of features! I took this for 4 days, and my headaches were unbearable. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Disclaimer. We comply with the HONcode standard for trustworthy health information. Isosorbide mononitrate Alternatives Compared - Drugs.com If this worries you, talk to your doctor or pharmacist about other options. This is called a medicine interaction. Yet many herbal supplements may interact with heart disease medicines. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. Other medications may be prescribed by your doctor for these conditions. Egton Medical Information Systems Limited. Prescription and OTC Do not double the dose to catch up. This risk may be even higher for certain groups. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? Isosorbide mononitrate belongs to the group of medicines called nitrates. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Registered in England and Wales. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Talk to your pharmacist for more details. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Natural Medicines. Isosorbide is in a class of medications called vasodilators. Follow directions about how much medicine to take. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Results: The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). information submitted for this request. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. coma (loss of consciousness for a period of time). isosorbide mononitrate, along with To use the sharing features on this page, please enable JavaScript. Change positions slowly until your body is used to the medication. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. It works by . Nitrates in the management of acute coronary syndrome. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Take extra precautions to avoid falling during your treatment with isosorbide. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). The use of the Truven Health products is at your sole risk. WebMD does not provide medical advice, diagnosis or treatment. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you forget to take a dose, take it as soon as you remember. You need to take it every day in order for it to work. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Isosorbide tablets are also used with other medications to treat heart failure. Keep all medications away from children and pets. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. A single copy of these materials may be reprinted for noncommercial personal use only. Talk to your provider if you notice your chest pain starts to get worse. Herbal supplements can strongly affect the body. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? MBBS, MS - General Surgery, mch neuro surgery. Saper RB. What should I know about storage and disposal of this medication? It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. Store in a cool, dry place, away from direct heat and light. If you have an eye condition called glaucoma. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. All rights reserved. Before Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Bethesda, MD 20894, Web Policies For details see our conditions. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Some of these interactions can be life-threatening. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Natural Medicines. If you become pregnant while taking isosorbide, call your doctor. It does not work fast enough to relieve the pain of an angina attack that has already started. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Cardizem may also be used for purposes not listed in this medication guide. Do not share this medication with others. The .gov means its official. https://naturalmedicines.therapeuticresearch.com. It can make you really dizzy. Take your next dose at the regular time. In: Textbook of Natural Medicine. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Should I avoid certain foods while taking Isosorbide Mononitrate? Do not change the dosing times unless directed by your doctor. May also be prescribed off label for Esophageal Spasm. Accessed Sept. 7, 2022. All rights reserved. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. health information, we will treat all of that information as protected health Consult your doctor before breast-feeding. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Isosorbide mononitrate works in two ways. Some of these medicine interactions can be risky. isosorbide mononitrate prices. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Nitroglycerin has an average rating of Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. This content does not have an English version. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Advertising revenue supports our not-for-profit mission. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Cardizem Alternatives Compared - Drugs.com Would you like email updates of new search results? Take the container with you, even if it is empty. We don't support your browser. Advertising revenue supports our not-for-profit mission. Real test is coronary angiography. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Mayo Clinic does not endorse companies or products. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Journals of the American College of Cardiology. Diabetes treatment: Can cinnamon lower blood sugar? https://naturalmedicines.therapeuticresearch.com. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Some don't work well with prescription medicines. Coenzyme Q-10 Natural Medicines. This does not necessarily mean no interactions exist. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. from the best health experts in the business. Copyright 2023 IBM Watson Health. Integrative medicine (complementary and alternative medicine). It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. If headaches continue or become severe, tell your doctor promptly. Consult your pharmacist or local waste disposal company. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. The extended-release tablet usually is taken once daily in the morning. This medicine is available only with your doctor's . Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. National Library of Medicine Are you looking for information on isosorbide dinitrate (Isordil) instead? Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. MeSH Moderately clinically significant. Am J Ther. The IR version can help treat and prevent angina. Please see a good cardiologist, get admitted, get checked thoroughly. Elsevier; 2021. https://www.clinicalkey.com. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. It can cause your blood pressure to become dangerously low. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". List of Antianginal agents (antianginal drugs) - Drugs.com Select a condition to view a list of medication options. Dated August 2017. Generic alternatives may be available. Accessed Sept. 7, 2022. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. . If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. May also be prescribed off label for Esophageal Spasm. [2] It is taken by mouth. The tablet usually is taken two or three times daily. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Please note that only the generic name of each medication is listed below. Does isosorbide mononitrate (Monoket) affect your kidneys? Is not subject to the Controlled Substances Act. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Available for Android and iOS devices. Sept. 26, 2022. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Properly discard this product when it is expired or no longer needed. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. No, that's not true all the time. This site needs JavaScript to work properly. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). This is called a medicine interaction. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx These side effects may go away during treatment as your body adjusts to the medicine. Portions of this document last updated: Feb. 01, 2023. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). The extended-release tablet usually is taken once daily in the morning. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Many common herbal supplements interact with common heart medicines. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Nitrate-induced headache in patients with stable angina pectoris All rights reserved. Ask your pharmacist for a list of the ingredients. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. US residents can call their local poison control center at 1-800-222-1222. Clipboard, Search History, and several other advanced features are temporarily unavailable. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. However, you should not flush this medication down the toilet. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. 2023 eHealthMe.com. Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx Hawthorn. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Herbal supplements and heart medicines may not mix - Mayo Clinic Canada residents can call a provincial poison control center. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. https://naturalmedicines.therapeuticresearch.com. All rights reserved. But only about 25% of people who take herbal supplements tell their health care providers. Accessed Sept. 7, 2022. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). Usually avoid combinations; use it only under special circumstances. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Almost 70% of older adults use them. Which drugs or supplements interact with isosorbide mononitrate? Click here for an email preview. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Changing positions slowly can help lessen dizziness. The table below contains some of the most common ones associated with isosorbide mononitrate. Call your doctor for medical advice about side effects. This is not a complete list of possible side effects. Last Revised - 09/15/2019. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). These headaches may be a sign that the medication is working as it should. Accessed Sept. 7, 2022. Try to keep your regular appointments with your doctor. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. If you are a Mayo Clinic patient, this could Accessed Sept. 7, 2022. In case of overdose, call the poison control helpline at 1-800-222-1222. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). B complex. Some products have ingredients that could worsen your heart failure. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. An official website of the United States government. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. Consult your doctor for more details. It is not intended as medical advice for individual conditions or treatment. All Rights Reserved. 7 disease interactions. See also: nitroglycerin side effects in more detail. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Some side effects may occur that usually do not need medical attention. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty It is important that you follow the instructions your doctor gives to you about when to take your doses. Continue to take isosorbide even if you feel well. Alcohol can make the side effects from isosorbide worse. Some conditions may become worse when the drug is suddenly stopped. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. Ginkgo. What are the side effects of Isosorbide Mononitrate ? Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Isosorbide mononitrate: isosorbide mononitrate. This is so your doctor can check on your progress. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Epub 2006 Mar 22. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain.
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